Showing posts with label B.PHARMACY 5TH SEM PAPERS. Show all posts
Showing posts with label B.PHARMACY 5TH SEM PAPERS. Show all posts
PHAR. CHEMISTRY -VI PY-503 SYLLABUS
Introduction to medicinal chemistry
- Principles of drug discovery: Basic principles of medicinal chemistry,physicochemical and steric aspects (optical, geometric and bioisosterism) of drug molecules and biological actions.
- Receptors and drug action: Receptor theories, affinity, receptor and biologic response.
- Drug metabolism: Phase I (biotransformation reactions), phase II (conjugation reactions), factor affecting drug metabolism.
- Prodrugs and drug latentiation: Basic concepts, prodrug of functional groups, bioprecursor prodrugs, chemical delivery system. Classification and mode of action, uses, structure activity relationship including physicochemical, steric aspects and resents advances in research of the following categories of drugs:
- Drugs affecting neurotransmission
- Drugs affecting cholinergic neuro transmission: Neuro chemistry and stereochemistry of acetylcholine, acetylcholine mimetics-muscarinic agonists,acetlycholinesterase inhibitors, acetylcholine antagonists-muscarinic anatagonists, nicotinc antagonists-neuromuscular blocking agents, ganglionic blocking agents.
- Drugs affecting adrenergic neurotransmission: Neurochemistry and stereochemistry of norepinephrine, sympathomimetic agents, sympatholytic agents, drugs affecting catecholamine biosynthesis, drugs affecting catecholamine storage and release, ergot alkaloids, xanthine bronchodilators
- Drugs affecting serotonergic neurotransmission: Neurochemistry and stereochemistry of serotonin, 5-HT agonists, 5-HT antagonists.
- Local anesthetics: Molecular mechanism of action, chemical aspects.
- Drugs affecting immune systems
- Non-steroidal anti-inflammatory agents: Chemistry of chemical mediators of inflammation (prostaglandins, thromboxanes, prostacyclin and leukotrienes), antipyretic analgesics.
- Antihistaminics and related antiallergics: Neurochemistry and stereochemistry of histamine, inhibitor of histamine release (mast cell stabilizers), inhibitors of released histamine, dual acting antihistaminics; H2 antagonists, H3 antagonists.
LIST OF PRACTICALS:
(Minimum fifteen experiments should be performed in the semester. Student should aware with safety parameters and handling of chemicals related to following experiments)
- Synthesis and characteriazation of Tropenone from Maleyde aldehyde.
- Synthesis and characteriazation of Scopolamine from Tropenol.
- Synthesis and characterization of chlorzoxazone from 2-amino-4-chlorphenol.
- Synthesis and characterization of Clemastine.
- Synthesis and characterization of Tripelennamine.
- Synthesis and characterization of Oxyphenbutazone.
- Synthesis and characterization of trihexyl phenylidine.
- Synthesis and characterization of Aspirin from salicylic acid.
- Synthesis and characterization of Benzimadazole from benzyl chloride.
- Synthesis and characterization of Sulphonilamide from Aniline.
- Synthesis and characterization of Paracetamol from Para amino phenol.
- Synthesis and characterization of Ibuprofen from isobutyl benzene.
- Synthesis and characterization of Antipyrine
- Synthesis and characterization of Phenyl benzoate.
- Synthesis and characterization of Benzenilide.
- Synthesis and characterization of Phenindione.
- Synthesis and characterization of Methyl pyrazolone.
BOOKS RECOMMENDED:
- Foye, W.C., Principles of Medicinal Chemistry, Lea and Febiger, Philadelphia.
- Wolff , M.E. Ed., Burger’s Medicinal Chemistry, John Wiley and Sons, New York.
- Hansch, C., Comprehensive Medicinal Chemistry, Pergarnon Press, Oxford.
- Delagado, J.N. and Remers, W.A.R, Wilson and Giswold’s Text Book of Organic,Medicinal and Pharmaceutical Chemistry, J.Lippincott Co., Philadelphia.
- Nogrady, T., Medicinal Chemistry-A Biochemical Approach, Oxford University Press, New York, Oxford.
- Kar, A., Medicinal Chemistry, Willey Eastern Ltd., New Delhi.
- Patrick, G., An Introduction to Medicinal Chemistry, Scientific Distributors, Mumbai.
- Malone, Dyson and Purey, May’s Chemistry of Synthetic Drugs.
- Parimoo, P., Text Book of Medicinal Chemistry, CBS Publishers and Distributors, New Delhi.
- Thomas, G., Introduction to Medicinal Chemistry, CBS Publishers and Distributors, New Delhi
DISPENSING, COMMUNITY AND HOSPITAL PHARMACY SYLLABUS
Dispensing Pharmacy:
Prescription,Handling of prescription,Sources of errors in prescription,Care required in dispensing prescriptions.Brief introduction of commonly used Latin terms in prescription. General Dispensing Procedures including labeling of dispensed products.Principles involved and procedures adopted in dispensing of typical prescriptions-Powders,Solutions, Mixtures, Emulsions, Lotions & Liniments.Physical, Chemical and Therapeutic incompatibilities, Incompatibility of common occurrence and their correction.Basis of posology, Detection of over doses in prescription, knowledge of prophylactic and therapeutic doses with route of administration.
Community Pharmacy:
Organization & structure of retail & wholesale drug stores,Legal requirements for establishment and maintenance. Dispensing of proprietary products,Maintenance of records of retail and wholesaler, Patient counseling, Role of Pharmacist in community health care and education, Hazards of medication. A brief study of propritory products available in the market belonging to Chemotherapeutic,Vitamins, Anti-histamines, expectorants and NSAID’S category.
Hospital Pharmacy:
Organization and structure: Organization of a hospital pharmacy, responsibilities of a hospital
pharmacist, pharmacy and therapeutic committee.Hospital Formulary: Contents, preparation and revision of hospital formulary.
Prescription,Handling of prescription,Sources of errors in prescription,Care required in dispensing prescriptions.Brief introduction of commonly used Latin terms in prescription. General Dispensing Procedures including labeling of dispensed products.Principles involved and procedures adopted in dispensing of typical prescriptions-Powders,Solutions, Mixtures, Emulsions, Lotions & Liniments.Physical, Chemical and Therapeutic incompatibilities, Incompatibility of common occurrence and their correction.Basis of posology, Detection of over doses in prescription, knowledge of prophylactic and therapeutic doses with route of administration.
Community Pharmacy:
Organization & structure of retail & wholesale drug stores,Legal requirements for establishment and maintenance. Dispensing of proprietary products,Maintenance of records of retail and wholesaler, Patient counseling, Role of Pharmacist in community health care and education, Hazards of medication. A brief study of propritory products available in the market belonging to Chemotherapeutic,Vitamins, Anti-histamines, expectorants and NSAID’S category.
Hospital Pharmacy:
Organization and structure: Organization of a hospital pharmacy, responsibilities of a hospital
pharmacist, pharmacy and therapeutic committee.Hospital Formulary: Contents, preparation and revision of hospital formulary.
LIST OF PRACTICALS:
- Prepare and Dispense Simple Powder.
- Prepare and Dispense Compound Powder.
- Prepare and Dispense Powder containing small doses.
- Prepare and Dispense Powder containing liquids.
- Prepare and Dispense Powder containing liquefiable substances.
- Prepare and Dispense Powder containing hygroscopic and deliquescent substances.
- Prepare and Dispense Powder containing efflorescent materials.
- Prepare and Dispense effervescent granules.
- Prepare and Dispense Dusting Powder.
- Prepare and Dispense Simple Mixture containing Soluble substances only.
- Prepare and Dispense Mixture containing Diffusible solids.
- Prepare and Dispense Mixture containing Indiffusible solids.
- Prepare and Dispense Mixture containing Precipitate forming liquids.
- Prepare and Dispense Mixture containing Slightly soluble liquids.
- Prepare and Dispense Mixture containing Small doses of potent medicaments.
- Prepare and Dispense prescription possessing Physical Incompability (Incomplete Solution).
- Prepare and Dispense prescription possessing Physical Incompability (Precipitation).
- Prepare and Dispense prescription possessing Physical Incompability (Separation of immiscible liquids).
- Prepare and Dispense prescription possessing Chemical Incompability (Alkaloidal salts with alkaline substances).
- Prepare and Dispense prescription possessing Chemical Incompability (Alkaloidal salts with soluble iodides).
- Prepare and Dispense prescription possessing Chemical Incompability (Alkaloidal salts with salicylates).
- Prepare and Dispense prescription possessing Chemical Incompability (Alkaloidal salts with benzoates).
- Prepare and Dispense prescription possessing Chemical Incompability (Soluble salicylates with acids-Tolerated Incompatability).
- Prepare and Dispense prescription possessing Chemical Incompability (Soluble salicylates with acids-Adjust Incompatability).
- Prepare and Dispense prescription possessing Chemical Incompability (Soluble benzoates with acids-Tolerated Incompatability).
- Prepare and Dispense prescription possessing Chemical Incompability (Soluble benzoates with acids-Adjusted Incompatability).
- Prepare and Dispense prescription possessing Chemical Incompability (Soluble salicylates with ferric salts).
- Prepare and Dispense prescription possessing Chemical Incompability (Soluble benzoates with ferric salts).
- Prepare and Dispense prescription possessing Chemical Incompability (Evolution of carbon dioxide).
- Prepare and Dispense prescription possessing Chemical Incompability of emulsifying agents.
- Prepare and Dispense Emulsion containing Volatile oils.
- Prepare and Dispense Emulsion containing Fixed oils.
- Prepare and Dispense Emulsion containing Oleoresins.
- Prepare and Dispense Calamine lotion.
- Prepare and Dispense turpentine liniment.
BOOKS RECOMMENDED:
- Allwodd M. C. and Fell J. T., Text book of Hospital Pharmacy, Blackwell Scientific Publication, Oxford.
- Hassan W. E., Lea and Febiger, Philadelphia Hospital Pharmacy.
- J.S. Qadry, R.K. Goyal & R.K. Parika, Merchant & Qadry’s a text book of Hospital Pharmacy, B.S. Shah Prakashan, Ahmedabad.
- Pratibha Nand & R.K. Khar, Text Book of Hospital & Clinical Pharmacy, Birla Publications Pvt Ltd., Delhi.
- S.J. Carter (Ed.), Cooper & Gunn’s Dispensing for Pharmaceutical Students, CBS Publishers & Distributors, New Delhi.
- R.M. Mehta, Dispensing Pharmacy, Vallabh Prakashan, Delhi.
- S.N. Sharma & N.K. Jain, the Concise Pharmaceutical Dispensing, Prakash B. Printers, Baroda.
- N.K. Jain & G.D. Gupta, Modern Dispensing Pharmacy, PharmaMed Press, Hyderabad.
- E.W. Martin, Dispensing of Medications (Formerly Husa’s Pharmaceutical Dispensing) Mack Publishing Company, Eastern Pa.
META TAGS:-RGTU B.PHARMACY 5TH SEM SYLLABUS I DOWNLOAD RGPV B.PHARMACY SYLLABUS I RGPV 5TH SEMESTER SYLLABUS I RGPV B.PHARMACY COSMETIC TECHNOLOGY SYLLABUS I PY-501 SYLLABUS I DISPENSING COMMUNITY AND HOSPITAL PHARMACY SYLLABUS I MEDICINAL CHEMISTRY SYLLABUS I PHARMACOGNOSY SYLLABUS I PHARMACOLOGY-II PY-505 I RGTU B.PHARMACY 5TH SEM PREVIOUS YEAR PAPERS I RGTU B.PHARMACY 5TH SEM PAPERS I B.PHARMACY 5TH SEM BOOKS I B.PHARMACY 5TH SEM SYLLABUS I DOWNLOAD RGPV B.PHARMACY 5TH SEMESTER SYLLABUS I RGTU B.PHARMACY SYLLABUS I RGPV B.PHARMACY SYLLABUS I RGTU PHARMACY 5TH SEM SYLLABUS I B.PHARMACY 5TH SEM REFERENCE BOOKS
B. PHARMA- V SEMESTER (Modified on 14/06/10)
Rajiv Gandhi Proudyogiki Vihswavidyalay, Bhopal (M.P.)
Rajiv Gandhi Proudyogiki Vihswavidyalay, Bhopal (M.P.)
