PHARMACOLOGY-II PY-505
Pathophysiology of CNS diseases and pharmacology of drugs used to treat them
1) Neuro humoral transmission in CNS
- Cholinergic pathways
- Dopaminergic pathway
- Serotonergic pathways
- Noradrenergic pathways
2) General anesthetics
3) Hypnotics, sedatives, antianxiety agents, and centrally acting muscle relaxants.
4) Psychopharmacological agents
- Antipsychotics
- Antidepressants
- Antimaniacs
- Hallucinogens
5) Anti-epileptic drugs
6) Narcotic analgesics and antagonist
7) Drugs used in neurodegenerative diseases
- Parkinson’s Disease
- Alzheimer’s Disease
8) Drug addiction and drug abuse
- Alcohol
- Nicotine
- Cannabis
9) CNS stimulants
Pharmacology of drugs acting on gastrointestinal tract
1) Antacids, antisecretory and antiulcer drugs
2) Emetics and antiemetics
LIST OF PRACTICALS
- Bioassay for acetylcholine/histamine using isolated organ preparations (rat ileum/rat duodenum/rat colon/rat fundus/guinea pig ileum/guinea pig tracheal chain preparation /goat ileum) : a) Matching bioassay or Bracketing bioassayb) Interpolation bioassay or graphical bioassay
- Study the CNS depressants using cornea and pinna reflex test.
- Study CNS stimulants by evaluation of locomotor activity (Actophotometer)
- Study Central muscle relaxants using Rota rod apparatus
- Study lenticular opacity produced by opioid analgesics in rodents.
- Study anticonvulant effect of some drugs using maximum electroshock method and chemical-induced convulsion method.
- Study antianxiety effect of some drugs using elevated plus maze test or social interaction test or novelty suppressed feeding test in rodents.
- Evaluate hypnotic activity of a drug by employing potentiation of thiopental induced sleeping time paradigm.
- Study antipsychotic effect of some drugs using catalepsy test or inhibition of amphetamine stereotypy in rodents. Study intravenous anesthetics using righting reflex test.
BOOKS RECOMMENDED:
- Herfindal, E.T., Gourley, D.R., (eds.) (2000) Textbook of therapeutics Drug and disease management. 7th ed. Baltimore: Lippincott Williams and Wilkins
- Hardmen, J.G., Limbird, L.E., Gilman A.,G., (eds.) (2001) Goodman and Gilman’s The pharmacological basis of therapeutics. 10th ed. USA: The McGraw Hill Companies
- Kumar, V., Abbas, A.K., Fausto, N., (eds.) (2004) Robbins and Cotran Pathologic basis of disease. 7th ed. Pennsylvania: Saunders
- Barar,F.S.K.,(2000) Essentials of therapeutics.New Delhi:S.Chand and Company (P) Ltd.
- Satoskar,R.S.,Bhandarkar,S.D.,Rege,N.N., (2007) Pharmacology and Pharmaco therapeutics. 12th ed. Mumbai: Popular Prakashan
- Seth, S.D., (ed.) (2005) Textbook of Pharmacology. 2nd ed. New Delhi. Elsevier
- Tripathi, K.D. (1999) Essentials of medical pharmacology. 4th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd.
- Mycek M.J.,Haney,R.A.,Champe,P.C.(2000) Lippincott’s illustrated reviews:Pharmacology. 2nd ed. Baltimore: Lippincott Williams and Wilkins.
- Rang, H.P., et al. (eds.) (2003) Pharmacology. 5th ed. Philadelphia: Elsevier
- Katzung,B.G.,(2004) Basic and clinical pharmacology. 9th ed.USA:The McGraw Hil Companies.
- McKim, W.A., (2006) Drugs and Behavior:An Introduction to Behavioral Pharmacology. London: Prentice Hall.
META TAGS:-RGTU B.PHARMACY 5TH SEM SYLLABUS I RGPV B.PHARMACY 5TH SEM PHARMACOLOGY SYLLABUS I PY-505 SYLLABUS I DOWNLOAD RGTU SYLLABUS I B.PHARMACY 5TH SEM SYLLABUS I B.PHARMACY 5TH SEM PAPERS I RGPV B.PHARMACY PREVIOUS YEAR PAPERS I B.PHARMACY EXPERIMENT LIST I B.PHARMACY NOTES I B.PHARMACY 5TH SEM REFERENCE BOOKS I LIST OF PRACTICAL FOR PHARMACOLOGY I PY-505 REFERENCE BOOKS I B.PHARMACY 5TH SEM REFERENCE BOOKS I RGPV 5TH SEM PHARMACOLOGY-II PAPERS I DOWNLOAD RGTU PAPERS I RGTU B.PHARMACY PAPERS I RGPV BHOPAL B.PHARMACY SYLLABUS I RGTU B.PHARMACY 5TH SEM SYLLABUS I RGTU B.PHARMACY 5TH SEM SYLLABUS I RGTU 5TH SEM SYLLABUS I RGPV BHOPAL B.PHARMACY SYLLABUS I DOWNLOAD RGTU PHARMACY SYLLABUS I RGTU PHARMACY PREVIOUS YEAR PAPERS I RGPV OLD EXAM PAPERS I RGTU B.PHARMACY OLD EXAM PAPERS I B.PHARMACY NOTES I I B.PHARMACY PHARMACOLOGY NOTES
0 comments